Eurospital

Eurospital manufactures and commercializes pharmaceutical products, medical and surgical devices, in vitro diagnostic devices, cosmetics, dietary products (gluten-free products and food supplements).

Eurospital covers a wide range of areas, including the in vitro diagnosis of celiac disease, autoimmune diseases, Helicobacter pylori, Chlamydia, and Mycobacteria infections, Invasive bacterial diseases, and Sexually Transmitted Diseases.

The Diagnostic Business Unit aims at combining the experience gained in the biological, immunological, and biotechnological fields with the information provided by international clinical networks, laboratory personnel, and industry experts to transform every input into ideas, products, and solutions thus meeting its customers’ needs.

Eu-Turbo Analyzer

Ready-to-use turbidimetric station for fecal markers analysis

A benchtop turbidimetric instrument to create an independent station dedicated to the analysis of Eurospital turbidimetric tests for the quantitative determination of fecal markers like calprotectin, pancreatic elastase, fecal occult blood and Helicobacter pylori antigen. After a quick and safe preanalytical extraction protocol, EasyCal tubes can be loaded directly inside the Eu-Turbo Analyzer and the results will be available in less than 10 minutes. Reagents can be left refrigerated on board and the 30-days curve stability allows an immediate analysis run.

Main features

Benchtop: 49 cm x 60 cm x 62 cm x 38 kg
apacitive liquid level detector
Needle shock sensor
Wash station for reusable cuvettes
Removable reagents trays
Removable samples tray with 60 numbered positions
EasyCal tube can be positioned directly inside the samples tray
Separated racks for controls and calibrators
Rotor with 80 washable cuvettes positions
Automatic pre-dilution up to 1:100
Refrigerated chamber for reagent onboard stability
Random / urgent test run
125 tests / hour
No carry-over (lower than 15 ppm)
Daily start-up automatically run: self-test, reader’s
Sampling needle automatically washed after each operation
PC connected via USB port
Ethernet LAN connection

Tests to Assess Intestinal Inflammation

Calprotectin Dosage: Non-Invasive Method For Assessing Intestinal Inflammation

CalFast XT, a non-invasive test developed by Eurospital

WHAT IS CalFast XT?

CalFast XT is a non-invasive test developed by Eurospital that allows the identification of subjects with symptoms related to chronic inflammatory bowel disease (IBD), including ulcerative colitis, Crohn’s disease and the so-called “indeterminate colitis”, in less than 20 minutes. CalFast XT determines the level of calprotectin present in the feces with a rapid, accurate and quantitative analysis.

DIAGNOSTIC PRINCIPLE

Until today, to evaluate the inflammatory state of the intestinal mucosa it was necessary to resort to invasive tests (colonoscopy and subsequent histological examination). Recently, the use of non-invasive markers has found more and more credit: among these, one of the most reliable and safe is the determination of fecal concentration of calprotectin, an antimicrobial protein present in neutrophils that, in the presence of inflammatory bowel processes, is released into the intestinal lumen and therefore can be detected in feces. The diagnostic principle of CalFast XT is based on the quantitative determination of calprotectin in the stool: in patients with Chronic Inflammatory Bowel Diseases (IBD), the level of calprotectin is in fact generally very high. In subjects with Irritable Bowel Syndrome (IBS), the level of calprotectin is instead much lower than that found in patients with the active disease, sometimes higher than the reference value but, in any case, always higher than that found in healthy subjects.

Calprest NG, the immunoenzymatic test from Eurospita

WHAT IS Calprest NG?

Calprest NG is the immunoenzymatic test from Eurospital that allows to verify, in an accurate and non-invasive way, the presence of an inflammatory state of the intestinal tract. Unlike other tests, Calprest NG uses recombinant calprotectin to achieve a more reliable performance and a higher range of fecal protein determination (up to 3000 mg/kg). Calprest NG permits the differential diagnosis between organic diseases (Inflammatory Bowel Disease – IBD) and functional diseases (Irritable Bowel Syndrome – IBS). If Calprest provides a negative result, it is almost completely safe to exclude an inflammation of the intestinal mucosa.

A SIMPLE AND ACCURATE TEST

Until today, to evaluate the inflammatory state of the intestinal mucosa it was necessary to resort to invasive tests (colonoscopy and subsequent histological examination). Recently, the use of non-invasive markers has found more and more credit: among these, one of the most reliable and safe is the determination of fecal concentration of calprotectin, an antimicrobial protein present in neutrophils that, in the presence of inflammatory bowel processes, is released into the intestinal lumen and therefore can be detected in feces. The diagnostic principle of Calprest NG is based on the quantitative determination of calprotectin in the stool: in patients with Chronic Inflammatory Bowel Diseases (IBD), the level of calprotectin is in fact generally very high. In subjects with Irritable Bowel Syndrome (IBS), the level of calprotectin is instead much lower than that found in patients with the active disease, sometimes higher than the reference value but, in any case, always higher than that found in healthy subjects. Calprest NG uses this marker to allow the identification of you patients with inflammation that need to undergo further analysis, being more accurate than common biochemical tests (VES, PCR).

What is EasyCal?

EasyCal is the most advanced and precise device to collect repeatable amounts of feces to be used both with the classic immunoenzymatic and rapid immunochromatographic methods.
EasyCal is a ready-to-use device consisting of a tube containing the extraction solution (2.8 ml) and a specially designed dipstick with seven horizontal grooves for sample collection. The special design allows a simple use with any type of feces (normal, liquid, not formed, dry).
After collecting the stool sample, the device is inserted into the blue separator that retains the excess of fecal samples, not needed for the test. Only the adequate amount of feces (56 mg) gets therefore dispersed into the extraction solution present in the tube.
Following a simple and fast protocol for calprotectin extraction, the separator can be unscrewed counterclockwise and replaced with a clean cap. The sample within the tube can then be immediately analyzed or frost at -20°C for subsequent tests. If an automated instrumentation is used, the device can be placed directly into the sample rack and processed.
Thanks to a continuous improvement of the product, there is now a new and optimized protocol for calprotectin extraction. The implementations decrease the procedure steps allowing to save precious execution time and making it even easier. The innovated device now has an increased storage time, either with or without the sample.

WHAT IS Calprest TURBO?

Calprest TURBO is the new approach Eurospital offers to verify, in an accurate and non-invasive way, the presence of an inflammatory state of the intestinal tract. Calprest TURBO is an immuniturbidimetric test that allows a high throughput of analyzed samples minimizing the errors thanks to the high automation of the clinical chemistry instruments.
Calprest TURBO permits the differential diagnosis between organic diseases (Inflammatory Bowel Disease – IBD) and functional diseases (Irritable Bowel Syndrome – IBS). If Calprest provides a negative result, it is almost completely safe to exclude an inflammation of the intestinal mucosa.

A SIMPLE AND ACCURATE TEST

Until today, to evaluate the inflammatory state of the intestinal mucosa it was necessary to resort to invasive tests (colonoscopy and subsequent histological examination).
Recently, the use of non-invasive markers has found more and more credit: among these, one of the most reliable and safe is the determination of fecal concentration of calprotectin, an antimicrobial protein present in neutrophils that, in the presence of inflammatory bowel processes, is released into the intestinal lumen and therefore can be detected in feces. The diagnostic principle of Calprest TURBO is based on the quantitative determination of calprotectin in the stool: in patients with Chronic Inflammatory Bowel Diseases (IBD), the level of calprotectin is in fact generally very high.
In subjects with Irritable Bowel Syndrome (IBS), the level of calprotectin is instead much lower than that found in patients with the active disease, sometimes higher than the reference value but, in any case, always higher than that found in healthy subjects. Calprest TURBO uses this marker to allow the identification of you patients with inflammation that need to undergo further analysis, being more accurate than common biochemical tests (VES, PCR).

WHAT IS CALPREST?

Calprest is the immunoenzymatic test from Eurospital that allows to verify, in an accurate and non-invasive way, the presence of an inflammatory state of the intestinal tract. Calprest permits the differential diagnosis between organic diseases (Inflammatory Bowel Disease – IBD) and functional diseases (Irritable Bowel Syndrome – IBS). If Calprest provides a negative result, it is almost completely safe to exclude an inflammation of the intestinal mucosa.

A SIMPLE AND ACCURATE TEST

Until today, to evaluate the inflammatory state of the intestinal mucosa it was necessary to resort to invasive tests (colonoscopy and subsequent histological examination). Recently, the use of non-invasive markers has found more and more credit: among these, one of the most reliable and safe is the determination of fecal concentration of calprotectin, an antimicrobial protein present in neutrophils that, in the presence of inflammatory bowel processes, is released into the intestinal lumen and therefore can be detected in feces. The diagnostic principle of Calprest is based on the quantitative determination of calprotectin in the stool: in patients with Chronic Inflammatory Bowel Diseases (IBD), the level of calprotectin is in fact generally very high. In subjects with Irritable Bowel Syndrome (IBS), the level of calprotectin is instead much lower than that found in patients with the active disease, sometimes higher than the reference value but, in any case, always higher than that found in healthy subjects. Calprest uses this marker to allow the identification of you patients with inflammation that need to undergo further analysis, being more accurate than common biochemical tests (VES, PCR).