WHAT IS Calprest NG?
Calprest NG is the immunoenzymatic test from Eurospital that allows to verify, in an accurate and non-invasive way, the presence of an inflammatory state of the intestinal tract. Unlike other tests, Calprest NG uses recombinant calprotectin to achieve a more reliable performance and a higher range of fecal protein determination (up to 3000 mg/kg). Calprest NG permits the differential diagnosis between organic diseases (Inflammatory Bowel Disease – IBD) and functional diseases (Irritable Bowel Syndrome – IBS). If Calprest provides a negative result, it is almost completely safe to exclude an inflammation of the intestinal mucosa.
A SIMPLE AND ACCURATE TEST
Until today, to evaluate the inflammatory state of the intestinal mucosa it was necessary to resort to invasive tests (colonoscopy and subsequent histological examination). Recently, the use of non-invasive markers has found more and more credit: among these, one of the most reliable and safe is the determination of fecal concentration of calprotectin, an antimicrobial protein present in neutrophils that, in the presence of inflammatory bowel processes, is released into the intestinal lumen and therefore can be detected in feces. The diagnostic principle of Calprest NG is based on the quantitative determination of calprotectin in the stool: in patients with Chronic Inflammatory Bowel Diseases (IBD), the level of calprotectin is in fact generally very high. In subjects with Irritable Bowel Syndrome (IBS), the level of calprotectin is instead much lower than that found in patients with the active disease, sometimes higher than the reference value but, in any case, always higher than that found in healthy subjects. Calprest NG uses this marker to allow the identification of you patients with inflammation that need to undergo further analysis, being more accurate than common biochemical tests (VES, PCR).